FELLOWS OF THE AACR ACADEMY: CHARTING THE FUTURE OF CANCER RESEARCH
Established in 2013, the AACR Academy recognizes and honors distinguished scientists whose major scientific contributions have propelled significant innovation and progress against cancer. While election as a Fellow of the AACR Academy (FAACR) highlights past and current accomplishments, the groundbreaking scientists who earn this honor continue to chart the future of cancer research. AACR Fellows provide advice and counsel to the organization’s leadership on critical scientific issues, using their combined expertise to advance the AACR’s mission.
Class of 2017 Induction
At a ceremony on the evening before the Annual Meeting in Washington, D.C., the 2017 class of Fellows of the AACR Academy was formally inducted. The class included (left to right): Carl H. June, MD; Michael B. Kastan, MD, PhD; Riccardo Dalla-Favera, MD; Nancy E. Davidson, MD; Karen H. Vousden, PhD; Vishva M. Dixit, MD; and Michael Karin, PhD.
Class of 2017
Sir Adrian P. Bird, PhD, FAACR
Welcome Trust Centre for Cell Biology
University of Edinburgh
Edinburgh, Scotland
For characterizing CpG islands and highlighting the role of DNA methylation in the regulation of gene expression and disease onset
Emmanuelle Charpentier, PhD, FAACR
Max Planck Institute for Infection Biology
Berlin, Germany
Umeå University
Umeå, Sweden
For elucidating the molecular mechanisms governing CRISPR-mediated viral immunity and for contributions to developing the CRISPR-Cas9 gene editing system
Riccardo Dalla-Favera, MD, FAACR
Institute for Cancer Genetics
Columbia University
New York, New York
For demonstrating the significance of proto-oncogenes and select genetic abnormalities including chromosomal translocations in lymphomagenesis
Nancy E. Davidson, MD, FAACR
Fred Hutchinson Cancer Research Center
Seattle Cancer Care Alliance
University of Washington
Seattle, Washington
For defining key molecular drivers of breast carcinogenesis and helping to establish new therapeutic approaches for the treatment of breast cancer
Vishva M. Dixit, MD, FAACR
Genentech, Inc.
South San Francisco, California
For uncovering the role of caspases and associated signaling molecules in death receptor-mediated cell death and immune responses
Jennifer A. Doudna, PhD, FAACR
University of California, Berkeley
Berkeley, California
For revealing bacterial mechanisms of viral immunity and for developing the CRISPR-Cas9 system used to manipulate genomic DNA
Carl H. June, MD, FAACR
University of Pennsylvania School of Medicine
Abramson Cancer Center
Philadelphia, Pennsylvania
For designing chimeric antigen receptor T cell immunotherapy for the treatment of refractory and relapsed chronic lymphocytic leukemia
Michael Karin, PhD, FAACR
University of California, San Diego
La Jolla, California
For categorizing how environmental stress, hormones, inflammation, and obesity activate key signaling pathways involved in cancer
Michael B. Kastan, MD, PhD, FAACR
Duke Cancer Institute
Duke University School of Medicine
Durham, North Carolina
For ascertaining key steps of the DNA damage response pathway, deciphering mechanisms of p53-mediated cell cycle inhibition, and for defining the role of ATM in modulating mitochondrial function, insulin signaling, and cellular metabolism
Tomas Lindahl, MD, FRS, FAACR
Francis Crick Institute
London, England
For advancing the understanding of DNA damage repair through his discovery of the process of base excision repair and for isolating and characterizing several key components of the DNA repair machinery
Paul L. Modrich, PhD, FAACR
Duke University Medical Center
Durham, North Carolina
For clarifying the mechanisms of DNA mismatch repair and demonstrating its role in the onset of various cancers including hereditary nonpolyposis colon cancer
Karen H. Vousden, PhD, FAACR
The Crick Institute
Cancer Research UK
London, England
For describing various p53 regulatory mechanisms involved in carcinogenesis, including MDM2 inhibition of p53 function and the role of PUMA in p53-mediated cell death
Scientific Achievement Awards
In 1961, the AACR established its first scientific award, partnering with Eli Lilly and Company to present the AACR G.H.A. Clowes Memorial Award. Named for G.H.A. Clowes, a founding member of the AACR and a past research director at Eli Lilly and Company, the award recognized an individual scientist for outstanding recent accomplishments in the field of basic cancer research. More than fifty years later, the AACR continues to recognize and reward excellence in all areas of cancer science.
The 2017 AACR Scientific Achievement Awards and Lectureships highlighted exceptional scientists at several points along the career continuum. For example, the inaugural AACR-Waun Ki Hong Award for Outstanding Achievement in Cancer Research—named in honor of Waun Ki Hong, MD, FAACR, an AACR Past President—was established to recognize the outstanding research of investigators who are 51 years of age or younger. The first recipient of the award, Roger S. Lo, MD, PhD, was honored for his contributions toward identifying the molecular underpinnings of metastatic melanoma and its response to therapy.
Early recognition of promising scientists and support throughout their careers fosters breakthrough discoveries that can shift scientific paradigms and ultimately improve the lives of cancer patients. One example of a scientist whose career changed the field is Mina Bissell, PhD, FAACR, recipient of the 2017 AACR Award for Lifetime Achievement in Cancer Research. Dr. Bissell, who was honored for her seminal discoveries in cell biology that launched the field of tumor microenvironment research, received the AACR G.H.A. Clowes Award in 1999—an acknowledgment of a burgeoning career that eventually transformed the field’s understanding of cancer initiation and progression.
2017 Award Recipients and Lecturers
Fifty-Seventh Annual AACR G.H.A. Clowes Memorial Award
Riccardo Dalla-Favera, MD, FAACR
Columbia University
Institute for Cancer Genetics
New York, New York
Twenty-Sixth Annual AACR-American Cancer Society Award for Research Excellence in Cancer Epidemiology and Prevention
Meir Stampfer, MD, DrPH
Harvard Medical School
Boston, Massachusetts
Twenty-Second Annual AACR-Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research
Judy E. Garber, MD, MPH, FAACR
Dana-Farber Cancer Institute
Harvard Medical School
Boston, Massachusetts
TWENTIETH PEZCOLLER FOUNDATION-AACR INTERNATIONAL AWARD FOR CANCER RESEARCH
David M. Livingston, MD, FAACR
Dana-Farber Cancer Institute
Boston, Massachusetts
Twentieth Annual AACR-Women in Cancer Research Charlotte Friend Memorial Lectureship
Anne-Lise Børresen-Dale, PhD, MD (hc)
Oslo University Hospital Institute for Cancer Research
Oslo, Norway
Fourteenth Annual AACR Award for Lifetime Achievement in Cancer Research
Mina J. Bissell, PhD, FAACR
Lawrence Berkeley National Laboratory
Berkeley, California
Thirteenth Annual AACR-Irving Weinstein Foundation Distinguished Lecture
Leonard I. Zon, MD
Harvard Medical School
Boston, Massachusetts
Twelfth Annual AACR-Minorities in Cancer Research Jane Cooke Wright Memorial Lectureship
Carol L. Brown, MD
Memorial Sloan Kettering Cancer Center
New York, New York
ELEVENTH ANNUAL AACR-MARGARET FOTI AWARD FOR Leadership and Extraordinary Achievements in Cancer Research
Carlo M. Croce, MD, FAACR
Ohio State University Comprehensive Cancer Center
Columbus, Ohio
Eleventh Annual AACR Award for Outstanding Achievement in Chemistry in Cancer Research
Craig M. Crews, PhD
Yale University
New Haven, Connecticut
Eleventh Annual AACR Princess Takamatsu Memorial Lectureship
Louis M. Staudt, MD, PhD
National Cancer Institute
Bethesda, Maryland
Eleventh Annual AACR Team Science Award
The International Liquid Biopsy Initiative Team
Luis A. Diaz, Jr., MD
Team Leader
Memorial Sloan Kettering Cancer Center
New York, New York
Nishant Agrawal, MD
University of Chicago Pritzker School of Medicine
Chicago, Illinois
Chetan Bettegowda, MD, PhD
Johns Hopkins University School of Medicine
Baltimore, Maryland
Frank Diehl, PhD
Sysmex Inostics
Hamburg, Germany
Peter Gibbs, MD
Royal Melbourne Hospital
Parkville, Victoria, Australia
Stanley R. Hamilton, MD
University of Texas MD Anderson Cancer Center
Houston, Texas
Ralph H. Hruban, MD
Johns Hopkins University School of Medicine
Baltimore, Maryland
Hartmut H. Juhl, MD, PhD
Indivumed
Hamburg, Germany
Isaac A. Kinde, MD, PhD
PapGene, Inc.
Baltimore, Maryland
Kenneth W. Kinzler, PhD, FAACR
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland
Martin A. Nowak, PhD
Harvard University
Cambridge, Massachusetts
Nickolas Papadopoulos, PhD
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland
David Sidransky, MD
Johns Hopkins Medical Institutions
Baltimore, Maryland
Jeanne Tie, MD
The Walter and Eliza Hall Institute of Medical Research
Parkville, Victoria, Australia
Victor E. Velculescu, MD, PhD
Johns Hopkins University School of Medicine
Baltimore, Maryland
Bert Vogelstein, MD, FAACR
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland
Ninth Annual AACR Outstanding Investigator Award for Breast Cancer Research, funded by SUSAN G. KOMEN®
Nicholas C. Turner, PhD, FRCP
Royal Marsden Hospital Institute of Cancer Research
London, England
NINTH ANNUAL AACR DISTINGUISHED LECTURESHIP IN BREAST CANCER RESEARCH
Jeffrey M. Rosen, PhD
Baylor College of Medicine
Houston, Texas
Eighth Annual AACR Distinguished Lecture on the Science of Cancer Health Disparities, funded by SUSAN G. KOMEN®
Julie R. Palmer, ScD
Boston University School of Public Health
Boston Medical Center Cancer Center
Boston, Massachusetts
FIFTH ANNUAL AACR-CRI LLOYD J. OLD AWARD IN CANCER IMMUNOLOGY
Olivera (Olja) J. Finn, PhD
University of Pittsburgh School of Medicine
University of Pittsburgh Cancer Institute
Pittsburgh, Pennsylvania
INAUGURAL AACR-WAUN KI HONG AWARD FOR OUTSTANDING ACHIEVEMENT IN CANCER RESEARCH
Roger S. Lo, MD, PhD
Jonsson Comprehensive Cancer Center
David Geffen School of Medicine at UCLA
Los Angeles, California